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Epithelioid osteosarcoma presenting as a rapidly expanding maxillary mass
Joseph Rinaggio1, Greg F Kewitt, H Stan McGuff
1Department of Diagnostic Sciences, University of Medicine and Dentistry of New Jersey--New Jersey Dental School, Newark, New Jersey, USA. rinaggjo@umdnj.edu
Head & Neck
|January 19, 2007
Summary
This study reports a rare, aggressive epithelioid osteosarcoma in the maxillofacial complex of a 50-year-old male. The malignant mesenchymal neoplasm presented as a rapidly growing mass in the maxilla.
Area of Science:
- Oncology
- Pathology
- Maxillofacial Surgery
Background:
- Osteosarcomas of the jaw are rare, accounting for less than 10% of all osteosarcomas.
- These tumors typically affect individuals in their late 30s to mid-40s.
- Common variants include osteoblastic, chondroblastic, and fibroblastic types.
Observation:
- A rapidly growing mass was noted in the maxilla of a 50-year-old male during a dental procedure.
- The mass significantly increased in size over several weeks despite various treatment attempts.
Findings:
- Radiographic imaging showed a mixed-density mass in the left maxilla.
- Histologic, immunohistochemical, and electron microscopy confirmed a malignant mesenchymal neoplasm.
- The tumor exhibited sheets of epithelioid and spindle cells with focal osteoid formation.
Implications:
- This case highlights the aggressive nature of epithelioid osteosarcoma in the maxillofacial region.
- Accurate diagnosis through advanced microscopy is crucial for rare jaw neoplasms.
- Understanding rare osteosarcoma variants is vital for effective treatment strategies.
