Epithelioid osteosarcoma presenting as a rapidly expanding maxillary mass
Related Experiment Video
Updated: Jul 17, 2026
Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Joseph Rinaggio1, Greg F Kewitt, H Stan McGuff
1Department of Diagnostic Sciences, University of Medicine and Dentistry of New Jersey--New Jersey Dental School, Newark, New Jersey, USA. rinaggjo@umdnj.edu
Background:
Osteosarcomas of the jaws account for less than 10% of reported neoplasms of this type. Patients with osteosarcoma in this region tend to be in the late-third to mid-fourth decades of life. The osteoblastic, chondroblastic, and fibroblastic variants constitute the majority of lesions.
Methods:
A mass was observed in the maxilla of a 50-year-old male who presented for a complete odontectomy. Over the ensuing weeks, the mass substantially increased in size, despite multimodality treatment efforts.
Results:
Radiographic findings revealed a mixed density mass of the left maxilla. Histologic, immunohistochemical, and electron microscopy examination of the tumor showed a malignant mesenchymal neoplasm consisting of sheets of epithelioid and spindle cells exhibiting focal osteoid formation.
Conclusions:
We report a rare and aggressive case of epithelioid osteosarcoma arising in the maxillofacial complex.
