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Updated: Jul 17, 2026

Isolation and Culture Expansion of Tumor-specific Endothelial Cells
Published on: October 14, 2015
Vascular endothelium summary statement III: Cancer prevention and control
Eddie Reed1, John Seffrin, Raffaella Giavazzi
1Division of Cancer Prevention and Control, NCCDPHP, CoCHP, Centers for Disease Control and Prevention, 4770 Buford Highway, Mailstop K52, Atlanta, GA 30341 USA. Ereed1@cdc.gov
Abstract:
The biology of vascular endothelium can be modulated through the use of pharmacologic agents. Whereas this has been explored to reasonable extent in cardiovascular disease, it is clear that the ability to modulate vascular endothelium for the purpose of cancer prevention is in its early stages. Among the unanswered questions, we do not understand under what circumstances such pharmacologic interventions might best be started; nor, how long such interventions might be used for a given individual. We present concepts for further exploration in the use of endothelial-active agents for cancer prevention and control; and, strategies for public health practice and research in this area.
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