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Within-subject variation of seminal parameters in men with infertile marriages
F Francavilla1, A Barbonetti, S Necozione
1Department of Internal Medicine, Andrology Unit, University of L'Aquila, L'Aquila, Italy. francavi@cc.univaq.it
Abstract:
As little information exists on the semen variability in infertile men, this study aimed at analysing the within-subject variability of semen from men with infertile marriages included in an intrauterine insemination (IUI) programme. Five ejaculates from each of 436 men (2180 specimens) were analysed. The within-subject coefficients of variation (CV(w)) were high for all parameters (semen volume, sperm concentration, forward motility and combined parameters), ranging from 0.73 for the total motile sperm count to 0.27 for the semen volume. Nevertheless, within-subject fluctuations were smaller than the between-subject variability, as indicated by high Intraclass Correlation Coefficient (ICC) values, which, however, significantly lowered when
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