Neurocardiogenic injury in neurovascular disorders

Alexander Kopelnik1, Jonathan G Zaroff

  • 1Division of Cardiology, Department of Medicine, University of California San Francisco, San Francisco, CA 94143, USA.

Critical Care Clinics
|January 24, 2007
PubMed

Insights

Cardiac injury is common after stroke, particularly subarachnoid hemorrhage. Treatment should prioritize the neurological condition, as cardiac injury is often reversible.

Area of Science:

  • Neuroscience
  • Cardiology
  • Neurology

Background:

  • Cardiac injury frequently complicates stroke, with aneurysmal subarachnoid hemorrhage being a primary focus of neurocardiogenic injury research.
  • Neurocardiogenic injury impacts stroke prognostication and treatment strategies.

Purpose of the Study:

  • To review the occurrence and implications of cardiac injury following stroke, differentiating between subarachnoid hemorrhage and ischemic stroke.
  • To discuss diagnostic and prognostic tools for neurocardiogenic injury.
  • To outline management priorities in stroke patients with cardiac complications.

Main Methods:

  • Review of existing literature on cardiac injury in stroke patients.
  • Analysis of diagnostic modalities such as echocardiography and cardiac biomarkers (troponin, B-type natriuretic peptide).
  • Evaluation of treatment recommendations for cardiac dysfunction in the context of neurological conditions.

Main Results:

  • Cardiac injury is prevalent post-stroke, especially after subarachnoid hemorrhage.
  • Echocardiography and biomarker screening aid prognostication.
  • Cardiac injury after subarachnoid hemorrhage is generally reversible, and cardiac catheterization is not routinely advised.
  • Ischemic stroke patients are more prone to coexisting heart disease.
  • Cardiac evaluation in brain death cases can enhance organ donation potential.

Conclusions:

  • Prioritizing neurological treatment is crucial, even with coexisting cardiac dysfunction in stroke patients.
  • Cardiac injury associated with subarachnoid hemorrhage is typically reversible.
  • Distinguishing cardiac injury patterns between stroke subtypes is important for management and organ donation efforts.

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