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Updated: Jul 17, 2026

An In Vivo Duo-color Method for Imaging Vascular Dynamics Following Contusive Spinal Cord Injury
Published on: December 31, 2017
Neurocardiogenic injury in neurovascular disorders
Alexander Kopelnik1, Jonathan G Zaroff
1Division of Cardiology, Department of Medicine, University of California San Francisco, San Francisco, CA 94143, USA.
Insights
Cardiac injury is common after stroke, particularly subarachnoid hemorrhage. Treatment should prioritize the neurological condition, as cardiac injury is often reversible.
Area of Science:
- Neuroscience
- Cardiology
- Neurology
Background:
- Cardiac injury frequently complicates stroke, with aneurysmal subarachnoid hemorrhage being a primary focus of neurocardiogenic injury research.
- Neurocardiogenic injury impacts stroke prognostication and treatment strategies.
Purpose of the Study:
- To review the occurrence and implications of cardiac injury following stroke, differentiating between subarachnoid hemorrhage and ischemic stroke.
- To discuss diagnostic and prognostic tools for neurocardiogenic injury.
- To outline management priorities in stroke patients with cardiac complications.
Main Methods:
- Review of existing literature on cardiac injury in stroke patients.
- Analysis of diagnostic modalities such as echocardiography and cardiac biomarkers (troponin, B-type natriuretic peptide).
- Evaluation of treatment recommendations for cardiac dysfunction in the context of neurological conditions.
Main Results:
- Cardiac injury is prevalent post-stroke, especially after subarachnoid hemorrhage.
- Echocardiography and biomarker screening aid prognostication.
- Cardiac injury after subarachnoid hemorrhage is generally reversible, and cardiac catheterization is not routinely advised.
- Ischemic stroke patients are more prone to coexisting heart disease.
- Cardiac evaluation in brain death cases can enhance organ donation potential.
Conclusions:
- Prioritizing neurological treatment is crucial, even with coexisting cardiac dysfunction in stroke patients.
- Cardiac injury associated with subarachnoid hemorrhage is typically reversible.
- Distinguishing cardiac injury patterns between stroke subtypes is important for management and organ donation efforts.
Abstract:
cardiac injury occurs frequently after stroke; and the most widely investigated form of neurocardiogenic injury is aneurysmal subarachnoid hemorrhage. Echocardiography and screening for elevated troponin and B-type natriuretic peptide levels may help prognosticate and guide treatment of stroke. Cardiac catheterization is not routinely recommended in subarachnoid hemorrhage patients with left ventricular dysfunction and elevated troponin. The priority should be treatment of the underlying neurologic condition, even in patients with left ventricular dysfunction. Cardiac injury that occurs after subarachnoid hemorrhage appears to be reversible. In contrast to subarachnoid hemorrhage patients, patients with ischemic stroke are more likely to have concomitant significant heart disease. For patients who develop brain death, cardiac evaluation under optimal conditions may help increase the organ donor pool.
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