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Updated: Jul 17, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
Assessment of acute reperfused myocardial infarction with delayed enhancement 64-MDCT
Timo Baks1, Filippo Cademartiri, Amber D Moelker
1Department of Cardiology, Erasmus Medical Center, Dr. Molewaterplein 40, Rotterdam, The Netherlands. t.baks@erasmusmc.nl
Objective:
The purpose of this study was to evaluate the utility of delayed enhancement 64-MDCT in the assessment of myocardial infarct size in a porcine model of acute reperfused myocardial infarction. CT can be used for noninvasive assessment of coronary artery stenosis, but to our knowledge, evaluation of myocardial viability in the subacute phase of acute myocardial infarction has not been validated. We performed delayed enhancement imaging on six domestic swine 5 days after reperfused acute myocardial infarction and assessed the relation between delayed enhancement patterns in vivo and the extent of viable and nonviable myocardium at postmortem histochemical analysis.
Conclusion:
Delayed enhancement imaging with 64-MDCT can be used for accurate assessment of the size of reperfused acute myocardial infarcts.
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