Related Experiment Video
Updated: Jul 17, 2026

Time-Resolved, Dynamic Computed Tomography Angiography for Characterization of Aortic Endoleaks and Treatment Guidance via 2D-3D Fusion-Imaging
Published on: December 9, 2021
Quantitative analysis of ECG-gated high-resolution contrast-enhanced MR angiography of the thoracic aorta
Elliott M Groves1, William Bireley, Karin Dill
1Department of Radiology, Northwestern University Feinberg School of Medicine, 676 N St. Clair St., Ste. 800, Chicago, IL 60611, USA.
Insights
Cardiac gating significantly enhances the sharpness of thoracic aorta images in contrast-enhanced MR angiography. This technique improves image quality for diagnosing vascular diseases.
Area of Science:
- Radiology
- Medical Imaging
- Cardiovascular Imaging
Background:
- Thoracic aorta imaging is crucial for diagnosing vascular diseases.
- Cardiac motion can cause blurring, reducing image quality in MR angiography.
- Evaluating imaging techniques to improve diagnostic accuracy is essential.
Purpose of the Study:
- To compare the image quality of thoracic aorta MR angiography with and without cardiac gating.
- To assess the impact of cardiac gating on image sharpness at various thoracic aorta levels.
Main Methods:
- Fifty patients underwent contrast-enhanced MR angiography using a 1.5-T system.
- Patients were divided into two groups: one with ECG gating, one without.
- Image sharpness was quantitatively evaluated by analyzing signal intensity profiles of the aortic wall.
Main Results:
- Cardiac gating significantly increased the sharpness of the ascending thoracic aorta in both patient groups.
- Quantitative analysis confirmed a statistically significant improvement (p < 0.005) with gating.
Conclusions:
- Cardiac gating substantially improves the sharpness of the ascending aorta, mitigating motion-induced blurring.
- High-resolution contrast-enhanced MR angiography with cardiac gating yields superior image quality for accurate vascular disease diagnosis.
Objective:
The purpose of this study was to evaluate the effect of cardiac gating on the quality of images of the thoracic aorta at various levels during contrast-enhanced MR angiography compared with MR angiography without cardiac gating.
Materials And Methods:
Fifty patients underwent high-resolution contrast-enhanced MR angiography on a 1.5-T whole-body system. The 50 patients were composed of two groups of 25 consecutive patients; one group underwent MR angiography with ECG gating and the other group underwent MR angiography without ECG gating. A sagittal (3D) gradient-echo fast low-angle shot (FLASH) sequence (TR/TE, 2.8/1.4; flip angle, 25 degrees; readout, 512; voxel size, 1.4 x 0.8 x 1.3 mm) with an asymmetric k-space scanning scheme in all three gradient axes was used, and 0.2 mmol/kg of gadopentetate dimeglumine was injected at 2 mL/s. Sharpness of the thoracic aorta was evaluated at three levels by generating a signal intensity profile across the aortic vessel wall and calculating the distance between two points along a line representing the slope of the signal intensity profile. Both sides of the intensity profile were analyzed and averaged and then used to calculate sharpness. An additional group of six patients was included who had undergone both a gated and an ungated sequence; results of this group were analyzed independently.
Results:
Quantitative analysis of the sharpness of the ascending thoracic aorta showed a significant increase in sharpness in both the 50-patient and six-patient groups (p < 0.005) with the addition of cardiac gating.
Conclusion:
Cardiac gating significantly improves the sharpness of the ascending aorta, a portion of the aorta that is subject to a great deal of blurring caused by cardiac motion. High-resolution contrast-enhanced MR angiography with cardiac gating can produce high quality images of the thoracic vasculature, thus enabling accurate diagnosis of vessel disease.
Related Concept Videos
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Acute Coronary Syndrome III: Diagnostic Studies
Imaging Studies for Cardiovascular System V: CT
Aneurysm II: Clinical Manifestations and Diagnostic Studies