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Updated: Sep 11, 2026

Use of Artificial Sputum Medium to Test Antibiotic Efficacy Against Pseudomonas aeruginosa in Conditions More Relevant to the Cystic Fibrosis Lung
Published on: June 5, 2012
[Antibiotics of an aromatic nature from Pseudomonas cepacia]
Abstract:
A raw antibiotic has been isolated from culture fluid of strain Pseudomonas cepacia 5798. It was methylated and separated into individual components using the column and thin-layer chromatography. The isolated substances possessed antimicrobial activity; two of them were studied more in detail by the UV-, IR- and PMR-spectroscopy methods. Results of the study of physicochemical properties of methyl derivatives of antibiotics from P. cepacia permit supposing that the latter are aromatic substances with nitrogen atoms in the side chain.
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