Related Experiment Video
Updated: Aug 2, 2026
05:59
Determining the Reactivity and Titre of Serum using a Haemagglutination Assay
Published on: January 29, 2010
[The determination of tetanus antitoxin by the latex agglutination reaction]
Mikrobiologicheskii Zhurnal
|May 1, 1993
Abstract:
A new method to detect the protective value of antitetanic antibody in latex agglutination test (LAT) has been described. The new method is highly sensitive and fast, and requires no special equipment. The optimal conditions of sensibilization, latex types, test providing procedure have been selected. New LAT detects approximately 0.0015 IU antitoxin per ml. This method can be used to determine the state of immunization of population against tetanus and to detect the protective antibodies in production series of human and horse antitetanic immunoglobulins.
Related Concept Videos
01:29Tetanus
Tetanus is a life-threatening neurological disorder characterized by persistent muscle contractions and spastic paralysis. It is caused by Clostridium tetani, a motile, Gram-positive, rod-shaped, obligate anaerobe. These bacteria produce terminal endospores, giving them a distinctive “lollipop” or “tennis-racket” appearance. They thrive in anaerobic environments, such as those found in deep puncture wounds.Once introduced into the body, the spores germinate into vegetative cells. These cells...
01:28Diphtheria
Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...