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Published on: August 9, 2024
Chest pain and subsequent consultation for coronary heart disease: a prospective cohort study
1Primary Care Musculoskeletal Research Centre, Keele University, Keele.
Insights
Self-reported chest pain, even without prior diagnosis, is a significant indicator of future coronary heart disease (CHD) consultations. This finding emphasizes the importance of recognizing chest pain symptoms for early CHD risk assessment.
Area of Science:
- Cardiology
- General Practice
- Public Health
Background:
- Chest pain is a critical, yet often unreported, early indicator of coronary heart disease (CHD).
- General practice records may not capture initial chest pain symptoms, potentially delaying CHD diagnosis.
Purpose of the Study:
- To investigate if self-reported chest pain predicts future consultations for coronary heart disease (CHD).
- To assess the predictive value of chest pain in individuals without a prior CHD diagnosis.
Main Methods:
- A population-based study involving a survey and 7-year follow-up via General Practitioner (GP) record linkage.
- The Rose angina questionnaire was administered to 4002 adults; GP records identified participants with no prior CHD consultation.
- Prospective comparison of CHD consultation incidence between participants with and without self-reported chest pain.
Main Results:
- A total of 2229 participants with no prior CHD consultation were included in the 7-year prospective study.
- 558 participants reported chest pain, with 103 meeting angina criteria.
- Individuals reporting chest pain showed a higher incidence of CHD consultations over 7 years, independent of age.
Conclusions:
- Self-reported chest pain serves as a valuable marker for future coronary heart disease (CHD) diagnosis.
- Further research is needed to establish the clinical utility of early identification based on chest pain symptoms.
Background:
Chest pain may not be reported to general practice but could be an important first sign of coronary heart disease (CHD).
Aims:
To determine whether self-reported chest pain predicts future consultation for CHD in those with no history of consultation for CHD.
Design Of Study:
Population-based study, with 7 year's follow up by GP record linkage.
Setting:
General practice in North Staffordshire.
Method:
A survey, including the Rose angina questionnaire, was mailed to 4002 adults. Linked GP records used to identify responders with no record of CHD (G3 Read code or British National Formulary code for nitrate use) in the 32 months before the survey to form the sample for a 7-year prospective study. 'Survival' was compared in those with and without self-reported chest pain up to the earliest date of GP diagnosis of CHD, death, or end of the study period.
Results:
The survey response was 65% and 2348 participants gave permission to access their GP records. Of these, 2229 had no prior consultation for CHD. From the questionnaire, 558 reported chest pain of which 186 reported exertional pain and 103 met the criteria for angina. When followed prospectively, incidence of CHD consultations was higher in those with any chest pain definition, compared with no pain, and continued to be so for 7 years subsequently. Although these associations were strongly age related, self-reported symptoms were found to be an independent risk factor for future consultation for CHD.
Conclusion:
This study highlighted that self-reported chest pain is a marker of future CHD. The usefulness of early identification of people with this symptom remains to be established.
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