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Updated: Jul 17, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
[Idiopathic interstitial pneumonias: from classification to diagnostic work-up]
C Müller-Mang1, L Stiebellehner, K Schmid
1Universitätsklinik für Radiodiagnostik, Medizinische Universität, Währinger Gürtel 18-20, A-1090, Wien, Austria. christina.mueller-mang@meduniwien.ac.at
Idiopathic interstitial pneumonias (IIP) are rare lung diseases. High-resolution CT imaging aids diagnosis by correlating lung anatomy with histologic patterns, but biopsy is often needed.
Area of Science:
- Pulmonary Medicine
- Radiology
- Pathology
Background:
- Idiopathic interstitial pneumonias (IIP) encompass seven distinct histologic entities.
- While rare, IIPs serve as models for secondary interstitial pneumonias.
- High-resolution computed tomography (HRCT) significantly advanced IIP imaging.
Purpose of the Study:
- To review the computed tomography (CT) patterns of Idiopathic Interstitial Pneumonias (IIP).
- To provide clinical and histological information for radiologists.
- To support the multidisciplinary approach in managing IIP.
Main Methods:
- Review of CT patterns associated with IIP.
- Correlation of CT morphology with histologic findings.
- Integration of clinical context in diagnostic interpretation.
Main Results:
- HRCT allows detailed delineation of lung anatomy, enabling correlation with IIP histologic patterns.
- CT morphology, combined with clinical information, can lead to accurate diagnosis in many IIP cases.
- Significant overlap exists between different IIP entities on CT.
Conclusions:
- Radiologists can achieve accurate IIP diagnoses using HRCT and clinical data.
- Complementary lung biopsy remains essential due to overlapping CT features.
- Understanding CT patterns is crucial for radiologists in the multidisciplinary care of IIP.
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