Related Experiment Videos
Chromium-cage complex as contrast agent in MR imaging--biodistribution studies of the [57Co]cobalt analogue
G E Jackson1, M J Byrne, G Blekkenhorst
1Department of Chemistry, University of Cape Town, Rondebosch, South Africa.
International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology
|January 1, 1991
Abstract:
The synthesis and T1 and T2 relaxivities of the Cr(III)-(NH2)-Sar-cage complex is reported. An outer-sphere relaxation mechanism is postulated for the relaxivity of the complex. Tissue distribution studies in mice using a [57Co]cobalt analogue as a radioactive tracer showed that the complex is excreted rapidly in the urine. Some renal uptake of the complex is seen. Appreciable uptake of labelled cage complex was observed in 3-methylcholanthrene induced murine rhabdomyosarcoma.