Related Experiment Video
Updated: Jul 17, 2026

Retropinacol/Cross-pinacol Coupling Reactions - A Catalytic Access to 1,2-Unsymmetrical Diols
Published on: April 4, 2014
Resorcinol derivatives from two Ardisia species
H A Nguyen1, H Ripperger, J Schmidt
1Institute of Chemistry, National Centre for Scientific Research of Vietnam, Nghia Do, Tu Liem, Hanoi.
Two new resorcinol derivatives, 2-methyl-5-(Z-nonadec-14-enyl)resorcinol and 5-(Z-nonadec-14-enyl)resorcinol, were isolated from Ardisia silvestris leaves. Their structures were elucidated, with the latter also found in Ardisia gigantifolia roots.
Area of Science:
- Phytochemistry
- Natural Product Chemistry
Background:
- Ardisia species are known sources of diverse bioactive compounds.
- Sterols and triterpenoids are commonly found in plant secondary metabolites.
Purpose of the Study:
- To isolate and elucidate the structures of novel compounds from Ardisia silvestris.
- To investigate the chemical constituents of Ardisia species.
Main Methods:
- Phytochemical analysis of Ardisia silvestris leaf extracts.
- Isolation and structural elucidation of natural products using spectroscopic techniques.
Main Results:
- Isolation of known sterols and triterpenoids.
- Identification of two novel resorcinol derivatives: 2-methyl-5-(Z-nonadec-14-enyl)resorcinol and 5-(Z-nonadec-14-enyl)resorcinol.
- Confirmation of 5-(Z-nonadec-14-enyl)resorcinol in Ardisia gigantifolia roots.
Conclusions:
- The study expands the knowledge of Ardisia species' chemical diversity.
- The identified resorcinol derivatives represent new natural products with potential for further investigation.
More Related Videos
07:12Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions
Published on: July 17, 2020
07:30A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
Published on: January 21, 2020
Related Concept Videos
Preparation of Diols and Pinacol Rearrangement
The reaction begins with transferring a proton from the acid catalyst to one of the hydroxyl groups, producing an oxonium ion.
Preparation of Aldehydes and Ketones from Carboxylic Acid Derivatives
Carboxylic acid derivatives like acid chlorides and esters are more easily reducible than the corresponding acids. The derivatives reduce in the presence of mild reducing agents to give aldehydes. Aldehydes can also be prepared by Rosenmund reduction, that is, the reduction of acid...
Nucleophilic Aromatic Substitution: Addition–Elimination (SNAr)
The reaction begins with an attack of the nucleophile on the carbon that holds the leaving group. This results in the delocalization of the π electrons over the ring carbons. The resonance interaction between the...
Alcohols from Carbonyl Compounds: Reduction
Catalytic hydrogenation is similar to the reduction of an alkene or alkyne by adding H2 across the pi bond in the presence of transition metal catalysts like Raney Ni, Pd–C, Pt, or Ru. Aldehydes and ketones can be reduced by this method, often under mild to moderate heat (25–100°C) and...
Nucleophilic Aromatic Substitution of Aryldiazonium Salts: Aromatic SN1
In the Sandmeyer reaction, for example, the diazonio group is replaced by a chloro, bromo, or cyano...
Vicinal Diols via Reductive Coupling of Aldehydes or Ketones: Pinacol Coupling Overview