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Bioactive pregnanes from Nerium oleander.

Liming Bai1, Liyan Wang, Ming Zhao

  • 1Graduate School of Science and Technology, Department of Chemistry and Chemical Engineering, Niigata University, Ikarashi, 2-8050, Niigata 950-2181, Japan.

Journal of Natural Products
|January 27, 2007
PubMed
Summary

Researchers isolated new pregnanes from Nerium oleander, investigating their anti-inflammatory, cytotoxic, and multidrug resistance-reversal activities. Compound 4 showed anti-inflammatory and cytotoxic effects, while compounds 1, 2, and 5 demonstrated multidrug resistance-reversal properties.

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