Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 17, 2026

The Diffusion of Passive Tracers in Laminar Shear Flow
08:01

The Diffusion of Passive Tracers in Laminar Shear Flow

Published on: May 1, 2018

Stream spreading in multilayer microfluidic flows of suspensions.

Mona Utne Larsen1, Nina C Shapley

  • 1Department of Chemical Engineering, Columbia University, 500 W. 120th Street, MC 4721, New York, New York 10027, USA.

Analytical Chemistry
|January 30, 2007
PubMed
Summary

This study quantifies fluid stream spreading in microfluidics. Viscosity contrast significantly impacts stream width, with particle suspensions showing unique behavior at high concentrations due to shear-induced migration.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Efficient synthesis of antiviral agent uprifosbuvir enabled by new synthetic methods.

Chemical science·2021
Same author

Improved antimicrobial potency through synergistic action of chitosan microparticles and low electric field.

Applied biochemistry and biotechnology·2012
Same author

Biocompatible nanoparticles trigger rapid bacteria clustering.

Biotechnology progress·2009
Same author

Imaging contrast effects in alginate microbeads containing trapped emulsion droplets.

Journal of magnetic resonance (San Diego, Calif. : 1997)·2007
Same author

Dialysis without membranes: how and why?

Blood purification·2004

Area of Science:

  • Fluid Dynamics
  • Microfluidics
  • Rheology

Background:

  • Multilayer microfluidic flows involve complex fluid interactions.
  • Understanding stream spreading is crucial for optimizing microfluidic device performance.
  • Viscosity contrast between adjacent fluid streams influences flow behavior.

Purpose of the Study:

  • To experimentally quantify the spreading of parallel streams in multilayer microfluidic flows.
  • To investigate the effect of viscosity contrast on stream width.
  • To analyze the behavior of Newtonian fluids and particle suspensions under varying viscosity ratios.

Main Methods:

  • Utilizing a microfluidic device where three streams converge into a single channel.
  • Employing fluorescence microscopy to track fluid interface locations.

More Related Videos

Protocol for Biofilm Streamer Formation in a Microfluidic Device with Micro-pillars
07:19

Protocol for Biofilm Streamer Formation in a Microfluidic Device with Micro-pillars

Published on: August 20, 2014

Separating Beads and Cells in Multi-channel Microfluidic Devices Using Dielectrophoresis and Laminar Flow
09:45

Separating Beads and Cells in Multi-channel Microfluidic Devices Using Dielectrophoresis and Laminar Flow

Published on: February 4, 2011

Related Experiment Videos

Last Updated: Jul 17, 2026

The Diffusion of Passive Tracers in Laminar Shear Flow
08:01

The Diffusion of Passive Tracers in Laminar Shear Flow

Published on: May 1, 2018

Protocol for Biofilm Streamer Formation in a Microfluidic Device with Micro-pillars
07:19

Protocol for Biofilm Streamer Formation in a Microfluidic Device with Micro-pillars

Published on: August 20, 2014

Separating Beads and Cells in Multi-channel Microfluidic Devices Using Dielectrophoresis and Laminar Flow
09:45

Separating Beads and Cells in Multi-channel Microfluidic Devices Using Dielectrophoresis and Laminar Flow

Published on: February 4, 2011

  • Testing Newtonian fluids and polymethylmethacrylate (PMMA) particle suspensions with varying viscosities and volume fractions.

    • Main Results:

    • The steady-state width of the center stream strongly depends on the viscosity ratio, showing a near power-law relationship.
    • Both Newtonian fluids and suspensions exhibited this dependence, but with differing slopes.
    • High-concentration suspensions (phi = 0.30) deviated from Newtonian behavior, unlike low-concentration suspensions.

    Conclusions:

    • Viscosity ratio is a key parameter governing stream spreading in multilayer microfluidics.
    • Shear-induced particle migration affects the rheological behavior of concentrated suspensions.
    • Microfluidic experiments provide insights into complex fluid dynamics influenced by particle suspensions.