Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chitosan tissue scaffolds by emulsion templating.

George V Franks1, Belinda Moss, David Phelan

  • 1Chemical and Biomolecular Engineering, University of Melbourne, Melbourne, VIC 3010, Australia. gvfranks@unimelb.edu.au

Journal of Biomaterials Science. Polymer Edition
|January 31, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tailoring the surface pore morphology of bioceramic scaffolds through colloidal processing for bone tissue engineering.

PloS one·2025
Same author

Hierarchically porous 3D-printed ceramic scaffolds for bone tissue engineering.

Biomaterials advances·2024
Same author

Aggregation and breakage dynamics of alumina particles under shear by coupled Computational Fluid Dynamics - Discrete Element Method.

Journal of colloid and interface science·2024
Same author

Solvent Effect on the Nanotextural Formation of Reduced Graphene Oxide Membranes.

Langmuir : the ACS journal of surfaces and colloids·2023
Same author

Corrigendum to "A review of 2023 adult immunization schedule updates" [Vaccine 41(16) (2023) 2631-2633].

Vaccine·2023
Same author

A review of 2023 adult immunization schedule updates.

Vaccine·2023

A new method creates porous chitosan gels with tunable pore size and porosity for potential use as tissue scaffolds. This technique allows for the fabrication of complex 3D shapes with controlled material properties.

Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Tissue Engineering

Background:

  • Chitosan is a versatile biopolymer with potential applications in tissue engineering.
  • Developing methods to control the porosity of chitosan-based materials is crucial for scaffold fabrication.
  • Existing methods may lack control over pore size and overall structure.

Purpose of the Study:

  • To develop a novel method for fabricating porous chitosan gels.
  • To achieve controllable pore size and volume fraction in chitosan scaffolds.
  • To assess the suitability of these gels for tissue engineering applications.

Main Methods:

  • An oil-in-water emulsion method was employed, incorporating chitosan and a temperature-activated cross-linking agent.
  • Complex shapes were formed by molding or injecting the emulsion, followed by thermal cross-linking at 75°C for 15 minutes.

Related Experiment Videos

  • Post-processing involved washing to remove oil and surfactant, followed by air drying and ethanol washing. Scanning electron microscopy (SEM) was used for characterization.

    • Main Results:

    • The method successfully produced porous chitosan gels with controllable pore characteristics.
    • Porosity was directly proportional to the oil phase content.
    • Pore size was effectively controlled by adjusting the oil droplet size, primarily influenced by surfactant concentration.

    Conclusions:

    • The developed emulsion method offers a reliable way to produce porous chitosan gels with tunable properties.
    • The fabricated chitosan gels are promising candidates for use as scaffolds in tissue engineering.
    • This technique enables the creation of complex 3D porous structures from chitosan.