Related Experiment Video
Updated: Jul 17, 2026
Production of Modified Autologous Conditioned Serum and Ex Vivo Assessment of Its Healing Potential in Murine Corneal Epithelium
Published on: March 24, 2023
[Use of autologous serum in ophthalmic practice]
J S López-García1, I García-Lozano, L Rivas
1Hospital Central de Cruz Roja, Madrid, España. docsantilopez@hotmail.com
Objective:
To establish a protocol for the use of autologous serum in the ophthalmic practice.
Methods:
Personal experience and a literature review.
Results:
The use of autologous serum, in eye drop form, has been reported as a new treatment for several ocular surfaces diseases. These products have biomechanical and biochemical properties similar to normal tears. They contain components such as fibronectin, vitamin A and growth factors that have an epitheliotrophic effect on the ocular surface epithelial cells.
Conclusions:
The clinical studies performed showed a variable efficacy, with the preparative process and use of the autologous serum eye drops varying considerably between different studies.
