Related Experiment Video
Updated: Jul 17, 2026

A Pre-Clinical Model of Synovitis Using Ex vivo Human Synovial Tissue with Preserved Function and Architecture
Published on: March 20, 2026
[Articular manifestations in Crohn's disease. A prospective study of 68 cases]
Hela Sahli1, Monia Fekih, Faten Landolsi
1Service de Rhumatologie, Hôpital la Rabta, Tunis, Tunise.
Unlabelled:
The study was aimed to evaluate the frequency and types of articular manifestations in a group of Crohn's disease patients, and to determine the risk factors.
Subjects And Methods:
We included 68 Crohn's disease patients. All patients had a complete rheumatological examination. Radiographs of the sacroiliac joints and lumbar spine were performed. 40 men and 28 women with a mean age of 31 years were included. Articular manifestations were observed in 41 patients. Twenty two patients suffered of peripheral articular manifestations: arthralgias in 18 patients and arthritis in 10 cases. Peripheral articular manifestation were significatly associated to ileal location of intestinal disease. Their frequency was of 41.3% in ileal location group versus 13.6% in colic location group (p = 0.02). Axial manifestations were observed in 32 patients: ankylosing spondylitis was diagnosed in 11 cases, undifferentiated spondylarthropathy in 7 patients, sacroiliitis in 10 cases, inflammatory back pain in 3 patients and enthesopathy in 1 case. The male sex and long duration of intestinal disease were two independants factors associated to axial manifestations.
Related Concept Videos
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease IV: Clinical Manifestations
Inflammatory Bowel Disease III: Crohn's Disease
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...