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Updated: Jul 17, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
05:23

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

Management of sickle cell disease during CABG surgery--a case report

Madan Mohan Maddali1, Muthukkumar Chettiar Rajakumar, Prasad Panduranga Vishnu

  • 1Department of Anesthesiology, Royal Hospital, Muscat, Sultanate of Oman. madan@omantel.net.om

Middle East Journal of Anaesthesiology
|February 1, 2007
PubMed

Insights

This case study details elective Coronary Artery Bypass Graft (CABG) surgery in a sickle cell disease (SCD) patient. Preoperative transfusions and careful management ensured an uneventful surgical outcome.

Area of Science:

  • Cardiovascular Surgery
  • Hematology
  • Anesthesiology

Background:

  • Sickle cell disease (SCD) presents unique challenges for major surgeries.
  • Coronary Artery Bypass Graft (CABG) surgery requires careful perioperative management in SCD patients.

Observation:

  • A male patient with SCD underwent elective CABG surgery.
  • Cardiopulmonary bypass was employed during the procedure.
  • Preoperative transfusions were administered to achieve hemoglobin A levels above 60%.

Findings:

  • The patient experienced an uneventful perioperative period.
  • Strict avoidance of hypoxia and acidosis was crucial for successful outcomes.
  • The institutional protocol for preoperative transfusions in SCD patients was successfully implemented.

Implications:

  • This case highlights a successful strategy for managing SCD patients undergoing CABG.
  • It underscores the importance of tailored preoperative protocols for high-risk surgical patients.
  • The findings support the use of preoperative transfusions to optimize hemoglobin levels in SCD patients undergoing major surgery.

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