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Ultra-Fast Amplicon-Based Next-Generation Sequencing in Non-Squamous Non-Small Cell Lung Cancer
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Ultra-Fast Amplicon-Based Next-Generation Sequencing in Non-Squamous Non-Small Cell Lung Cancer

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[Diagnosis of lung cancer. DNA microarrays in thoracic oncology]

D Moro-Sibilot1, S Diab, S Lantuejoul

  • 1Groupe de Recherche sur les Cancers Bronchiques, INSERM U578, DMAS Pneumologie et Departement de Pathologie, Grenoble, France.

Revue Des Maladies Respiratoires
|February 3, 2007
PubMed

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DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...