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[Trachoma and the conjunctival impression test].

S Resnikoff1, R Castan, S Bonnet

  • 1Institut d'Ophtalmologie, Tropicale de l'Afrique, Bamako, Mali.

Revue Internationale Du Trachome Et De Pathologie Oculaire Tropicale Et Subtropicale Et De Sante Publique : Organe De La Ligue Contre Le Trachome Avec La Collaboration De L'International Organization Against Trachoma Et Des Organisation
|January 1, 1991
PubMed
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The Transferred Conjunctival Impression test (TCI) identifies Xerophthalmia risk in children. However, trachoma significantly impacts TCI results, showing a 1.7x higher abnormal rate in affected children.

Area of Science:

  • Ophthalmology
  • Public Health
  • Nutritional Science

Context:

  • Xerophthalmia remains a significant public health concern, particularly in resource-limited settings.
  • The Transferred Conjunctival Impression (TCI) test offers a non-invasive method for identifying at-risk populations.
  • Conjunctival pathology, such as trachoma, may influence the accuracy of the TCI test.

Purpose:

  • To evaluate the influence of trachoma on the results of the Transferred Conjunctival Impression test in children.
  • To quantify the relationship between trachoma and abnormal TCI test results in a Sahelian population.

Summary:

  • A trial involving 450 children aged 4-6 in the Sahelian zone assessed the TCI test's performance.
  • Results indicated that children with trachoma had a 1.7 times higher rate of abnormal TCI tests compared to non-trachomatous children, after controlling for age, residence, and nutritional status.

Related Experiment Videos

  • Conjunctival deficit was more frequent in trachomatous subjects.

    • Impact:

    • The TCI test is particularly useful in areas with low trachoma prevalence.
    • In regions with high trachoma prevalence, concurrent eye examinations are recommended to differentiate results between trachomatous and non-trachomatous children.
    • The study provides formulae for adjusting TCI test estimates when separate trachoma data is unavailable.