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Related Concept Videos

Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
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Updated: Jun 30, 2025

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
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Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment

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[Invasive squamous cell carcinoma: about 2 cases].

I Bamanta1, N Guirou2, O Touré2

  • 1Hôpital Sominé Dolo Mopti, Mali.

Le Mali Medical
|March 22, 2024
PubMed
Summary
This summary is machine-generated.

Squamous cell carcinoma of the conjunctiva, a rare malignant tumor, can invade the cornea. Surgical excision and examination confirmed the diagnosis in two Malian patients, with favorable outcomes.

Keywords:
CarcinomaCarcinomeConjonctiveConjunctivaEpidermoïdeExcisionExposition solaireExérèseSquamous cell carcinomaSun exposure

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Area of Science:

  • Ophthalmology
  • Oncology
  • Dermatology

Context:

  • Conjunctival tumors are prevalent in tropical regions with high UV exposure.
  • Malignant conjunctival tumors are rare, with squamous cell carcinoma being the most common.
  • Ophthalmology department of Sominé Dolo hospital in Mopti, Mali.

Purpose:

  • To report two cases of invasive squamous cell carcinoma of the conjunctiva.
  • To describe the clinical presentation, surgical management, and histopathological findings.
  • To highlight the importance of early diagnosis and treatment in high-risk populations.

Summary:

  • Two patients (25 and 51 years old) from a rural desert area presented with invasive conjunctival squamous cell carcinoma.
  • Clinical presentation included a corneal-invading mass preventing palpebral occlusion, characterized by a raised, multi-lobulated, pearly white, papillomatous appearance.
  • Wide surgical excision followed by anatomopathological examination confirmed mature, invasive, differentiated squamous cell carcinoma. Extension workup and HIV serology were negative.

Impact:

  • This case report contributes to understanding the clinical spectrum and management of conjunctival squamous cell carcinoma in underrepresented regions.
  • Successful surgical management resulted in a favorable medium-term outcome without recurrence.
  • Emphasizes the need for increased awareness and accessibility to ophthalmic care for early detection and treatment of ocular surface malignancies.