Countercurrent chromatography for the purification of peptides

In Table 3 are listed the types of peptides separated by CCC, including the instruments used and the solvent conditions. In the last 20 years, intriguing discoveries about the hydrodynamic behavior of liquids in open-coiled tubing have introduced many possibilities for chromatographic separations. A fruitful area of endeavor certainly lies in further elucidation of the mechanisms. However, it is evident that CCC has the capability to separate all types of substances: organic compounds, proteins, membrane proteins, subcellular particles, as well as peptides, the intermediate-sized molecules. The potential for applications also lies at various levels of the scale such as analytical, laboratory, and, very importantly, industrial processes.