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Updated: Jul 17, 2026

Evaluation of the Feasibility, Safety, and Accuracy of an Intraoperative High-intensity Focused Ultrasound Device for Treating Liver Metastases

Evaluation of the Feasibility, Safety, and Accuracy of an Intraoperative High-intensity Focused Ultrasound Device for Treating Liver Metastases

Published on: January 9, 2019

A device for radiofrequency assisted hepatic resection.

D Haemmerich¹, D J Schutt, J A Will

¹Dept. of Biomed. Eng., Wisconsin Univ., Madison, WI, USA.

Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference

|February 3, 2007

Summary

This study introduces a novel radiofrequency (RF) device designed to minimize blood loss during hepatic resection surgery. The RF electrode array effectively coagulates tissue and large vessels, reducing complications and improving patient outcomes.

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Area of Science:

Surgical Oncology
Biomedical Engineering
Hepatobiliary Surgery

Background:

Hepatic resection is standard for liver tumors but involves significant blood loss (approx. 1 L).
High blood loss correlates with increased complications, longer hospital stays, and reduced survival, particularly when transfusions are needed.

Purpose of the Study:

To present a novel device for minimizing blood loss during hepatic resection.
To enable surgical dissection along a pre-coagulated tissue plane, including large vessels.

Main Methods:

Development of a prototype device with a linear array of radiofrequency (RF) electrodes.
Application of bipolar RF current between adjacent electrodes to achieve localized tissue coagulation (approx. 100°C).
Rapid switching of current across electrode pairs to create a coagulated tissue slice.

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Evaluation of the Feasibility, Safety, and Accuracy of an Intraoperative High-intensity Focused Ultrasound Device for Treating Liver Metastases

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Main Results:

The device demonstrated effective coagulation of tissue planes and large vessels.
Ex vivo and in vivo experiments confirmed the device's functionality in reducing blood loss during simulated hepatic resection.

Conclusions:

The presented RF device offers a promising approach to significantly reduce intraoperative blood loss in hepatic resection.
This technology has the potential to improve patient safety and outcomes by minimizing transfusion requirements and surgical complications.