Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Microfluidic system integration in sample preparation chip-sets - a summary.

P Grodzinski1, R Liu, J Yang

  • 1Biosci. Div., Los Alamos Nat. Lab., NM, USA.

Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
|February 3, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transfection of IFNalpha in human glioblastoma cells and tumorigenicity in association with induction of PKR and OAS gene expression.

Journal of neurosurgery·1996
Same author

In vitro transcriptional analysis of TyrR-mediated activation of the mtr and tyrP+3 promoters of Escherichia coli.

Journal of bacteriology·1996
Same author

Case report: ranitidine-induced bradycardia in a patient with dextrocardia.

The American journal of the medical sciences·1996
Same author

Antioxidant-sensitive regulation of inflammatory-response genes in Kaposi's sarcoma cells.

Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association·1996
Same author

Cytokine expression in the presence or absence of late airway responses after antigen challenge of sensitized rats.

American journal of respiratory cell and molecular biology·1996
Same author

Injuries of the abdominal aorta and inferior vena cava in association with thoracolumbar fractures: a lethal combination.

The Journal of trauma·1996
Same journal

Highly Articulated Robotic Probe for Minimally Invasive Surgery.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference·2010
Same journal

Combined peripheral and cortical neural stimulation in motor neurorehabilitation.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference·2008
Same journal

Embedded assessment algorithms within home-based cognitive computer game exercises for elders.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference·2008
Same journal

Digital signal processing of the wideband external pulse recorded during cuff deflation: a new way to measure blood pressure.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference·2008
Same journal

Immune cells detection of the in vivo rejecting heart in USPIO-enhanced magnetic resonance imaging.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference·2008
Same journal

wHospital: a web-based application with digital signature for drugs dispensing management.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference·2007
See all related articles

New strategies integrate microfluidic chips for better biochemical assays. This review focuses on polymer chip-sets for cell pre-concentration using immunomagnetic separation in diagnostic systems.

Area of Science:

  • Biomedical Engineering
  • Analytical Chemistry
  • Materials Science

Background:

  • Microfluidic chips are increasingly complex for biochemical assays.
  • Integrating these chips into diagnostic systems is crucial for assay performance.

Purpose of the Study:

  • To review strategies for integrating microfluidic chips into diagnostic fluidic systems.
  • To highlight the selection of assay applications, integration schemes, interfacing, and fabrication platforms.
  • To discuss a specific system for cell pre-concentration from complex matrices.

Main Methods:

  • Review of existing literature on microfluidic integration.
  • Analysis of different integration schemes and fabrication platforms.
  • Focus on polymer microfluidic chip-sets and immunomagnetic separation techniques.

Related Experiment Videos

Main Results:

  • Identified key considerations for microfluidic chip integration: assay type, integration method, interface design, and fabrication.
  • Demonstrated the potential of polymer microfluidic chip-sets for cell pre-concentration.
  • Highlighted immunomagnetic separation as an effective method for sample preparation.

Conclusions:

  • Effective integration of microfluidic chips is essential for optimizing biochemical assay performance.
  • Polymer-based microfluidic systems offer a viable platform for advanced diagnostic applications.
  • Cell pre-concentration using immunomagnetic separation is a key step in preparing complex biological samples.