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Assessing Pupil-linked Changes in Locus Coeruleus-mediated Arousal Elicited by Trigeminal Stimulation
Published on: November 26, 2019
A method for size estimation of amorphous pupil in 3-dimensional geometry
Jieun Kim1, Kyungmo Park, Gon Khang
1Dept. of Biomed. Eng., Kyunghee Univ., Kyunggi, South Korea.
Summary
Accurately measuring pupil size noninvasively evaluates autonomic nervous system (ANS) activity. This study introduces a novel 3D eye model and estimation method for precise pupil size calculation from 2D images, offering an alternative to pupillometers and eye trackers.
Area of Science:
- Ophthalmology
- Neuroscience
- Biomedical Engineering
Background:
- Pupil size measurement is a noninvasive indicator of autonomic nervous system (ANS) activity.
- Current methods like pupillometry and eye tracking have limitations.
- A novel, accurate pupil size calculation method is needed for better ANS evaluation.
Purpose of the Study:
- To propose an accurate pupil size estimation method.
- To present a three-dimensional (3D) model of the eye and pupil.
- To offer an alternative to existing pupillometry and eye-tracking techniques.
Main Methods:
- Development of a 3D eye and pupil model.
- Image processing techniques to estimate pupil size from 2D projections.
- Accounting for image distortions in the calculation.
Main Results:
- A novel method for accurate pupil size estimation was developed.
- The 3D model aids in understanding pupil projection.
- The method provides an alternative to traditional tools for ANS assessment.
Conclusions:
- The proposed method offers a new approach for noninvasive ANS activity evaluation.
- Accurate pupil size calculation is feasible using the developed 3D model and estimation technique.
- This research contributes to objective physiological monitoring.
