Senciltrade mark project: development of a percutaneous optical biosensor.

Area of Science:

• Biomedical Engineering
• Chemical Sensing
• Optical Technologies

Background:

• Frequent in vivo analyte monitoring is crucial for managing various health conditions.
• Existing monitoring methods can be invasive, costly, or lack long-term stability.
• There is a need for reliable, disposable sensors for continuous physiological measurements.

Purpose of the Study:

• To introduce a novel, minimally invasive chemical sensor technology for long-term in vivo analyte monitoring.
• To detail the design, fabrication, and biocompatibility of this new sensor.
• To demonstrate its initial application in detecting analytes within a biological system.

Main Methods:

• Development of a disposable sensor utilizing photonic sensing principles.
• Implantation of a percutaneous optical fiber with a polymer matrix containing the sensing chemistry.
• Fabrication process focused on creating a robust and easily readable sensor.
• Biocompatibility testing to ensure safety for chronic implantation.

Main Results:

• Successful design and fabrication of the novel chemical sensor.
• Demonstrated biocompatibility of the implanted optical fiber sensor.
• Initial successful application showcasing the sensor's ability for in vivo measurements.
• The sensor is designed for 1-3 months of continuous monitoring.

Conclusions:

• The developed chemical sensor technology offers a promising solution for minimally invasive, long-term in vivo analyte monitoring.
• Its disposable nature and ease of reading facilitate frequent measurements.
• This technology has potential applications in various biomedical fields requiring continuous physiological data.