A respiration monitor based on electrocardiographic and photoplethysmographic sensor fusion

Respiratory variations are present in the pulse wave transit time (PTT) and, as a consequence of respiratory sinus arrhythmia, in the electrocardiogram (ECG) and the photoplethysmogram (PPG). The aim of this study was to investigate these variations in healthy subjects during rest and invoked blood pressure changes. The primary goal was to develop a non-invasive respiration monitor. The error rates for breath detection during rest were 14%, 11% and 10% for PTT, ECG and PPG respectively. Significantly higher error rates were found in hypotension and hypertension. To improve accuracy and robustness, the signals were merged in a neural network resulting in an error rate of 9%.