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Published on: November 14, 2012
Bilateral putaminal necrosis due to methanol abuse
M Dujardin1, E Peeters, C Ernst
1Department of Radiology/BEFY, Vrije Universiteit Brussel, Laarbeeklaan 101, B-1090 Brussels, Belgium. martine.dujardin@gmail.com
Summary
Methanol toxicity typically causes symmetrical basal ganglia lesions. This case highlights chronic methanol ingestion, showing characteristic MRI findings and previously unreported necrotic sequelae on late diffusion and post-contrast imaging.
Area of Science:
- Neurology
- Radiology
- Toxicology
Background:
- Methanol poisoning is a serious condition often diagnosed via characteristic brain imaging.
- Symmetrical basal ganglia lesions are the hallmark radiological sign of methanol toxicity.
Observation:
- A case of chronic, deliberate, and repeated methanol ingestion is presented.
- The study details typical magnetic resonance imaging (MRI) findings in the basal ganglia.
Findings:
- Characteristic MRI findings on T1, T2, FLAIR, and diffusion-weighted images were observed.
- This is the first reported case demonstrating late diffusion and post-contrast MRI changes indicating necrotic sequelae from methanol ingestion.
Implications:
- This case expands the understanding of radiological manifestations in chronic methanol toxicity.
- The findings emphasize the utility of advanced MRI techniques in diagnosing and assessing the long-term effects of methanol poisoning.
