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Updated: Jul 16, 2026

Enhanced Northern Blot Detection of Small RNA Species in Drosophila Melanogaster
Published on: August 21, 2014
New small nuclear RNA gene-like transcriptional units as sources of regulatory transcripts
Aldo Pagano1, Manuele Castelnuovo, Federico Tortelli
1Dipartimento di Oncologia Biologia e Genetica, Università di Genova, Genoa, Italy. aldo.pagano@istge.it
Abstract:
By means of a computer search for upstream promoter elements (distal sequence element and proximal sequence element) typical of small nuclear RNA genes, we have identified in the human genome a number of previously unrecognized, putative transcription units whose predicted products are novel noncoding RNAs with homology to protein-coding genes. By elucidating the function of one of them, we provide evidence for the existence of a sense/antisense-based gene-regulation network where part of the polymerase III transcriptome could control its polymerase II counterpart.
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