Related Experiment Video
Updated: Jul 17, 2026

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
Published on: March 3, 2023
Nasal symptoms and signs in children suffering from asthma
S K Steinsvåg1, B Skadberg, K Bredesen
1Department of Otorhinolaryngology, Head and Neck Surgery, Sørlandet Hospital, Kristiansand, Norway. sverre.steinsvag@sshf.no
Insights
Asthmatic children often experience upper airway issues like nasal blockage and mouth breathing. Enlarged adenoids may contribute to airway obstruction in these children, impacting their respiratory health.
Area of Science:
- Pediatric Allergy and Immunology
- Otolaryngology
- Respiratory Medicine
Background:
- A connection between upper and lower airways is established in health and disease.
- The role of the nose in pediatric asthma remains under-investigated.
Purpose of the Study:
- To compare upper airway symptoms and signs in children with asthma versus healthy children.
- To investigate the potential involvement of the nose and epipharynx in pediatric asthma.
Main Methods:
- Compared 27 asthmatic children with 29 age/sex-matched healthy controls.
- Utilized ENT specialist evaluations, parent questionnaires, skin prick tests, total IgE, acoustic rhinometry, and epipharyngeal X-rays.
- Analyzed and compared data between asthmatic and control groups.
Main Results:
- Asthmatic children showed higher prevalence of nasal blockage, mouth breathing, daytime sleepiness, apneas, itching, sneezing, and hearing impairment (p<0.05).
- Mean VAS scores for nasal blockage and daytime sleepiness were significantly higher in asthmatics.
- Asthmatics had a larger adenoid-nasopharynx-index, indicating reduced palatal airway (p<0.05).
Conclusions:
- Upper airway obstruction in asthmatic children appears localized to the epipharynx.
- Adenoids likely play a crucial role in the pathophysiology of pediatric asthma.
Objective:
A link between the upper and lower airways has been convincingly demonstrated both in health and disease. To what extent the nose may be involved in children's asthma, has so far not been thoroughly investigated. In this study, we compared symptoms and signs from the upper airways in children with asthma and in children without to find out more about this.
Methods:
The study group included 27 asthmatic children, the control group 29 age and sex-matched healthy volunteers. The children were investigated by a senior ENT-specialist. Their parents completed questionnaires about symptoms and signs of upper airway disorders. Skin prick tests, total IgE, acoustic rhinometry, and an X-ray of the epipharynx were performed. The data from the groups were compared.
Results:
Nasal blockage, mouth breathing, day time sleepiness, apnoeas, itching, sneezing, and hearing impairment were more prevalent in asthmatics compared with controls (p<0.05). For nasal blockage the mean VAS-scores were 52.4 and 30.6 for asthmatics and controls, respectively. For daytime sleepiness the corresponding figures were 34.6 and 23.1. The adenoid-nasopharynx-index was larger, indicating reduced palatal airway in the former compared with the latter (p<0.05).
Conclusions:
As the site of upper airway obstruction in asthmatic children appears to be the epipharynx, the adenoids may play a key-role.
Related Concept Videos
Asthma III: Clinical Manifestations
Asthma-III: Symptoms and Complications
Classification of Asthma
Asthma I: Introduction
Asthma-I: Introduction
Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
