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A helping hand for cytochrome p450 enzymes.

Russell A Debose-Boyd1

  • 1Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. russell.debose-boyd@utsouthwestern.edu

Cell Metabolism
|February 6, 2007
PubMed
Summary

The hemoprotein Dap1/PGRMC1 stabilizes and enhances cytochrome P450 enzyme activity. This interaction is crucial for P450-catalyzed reactions, impacting sterol and drug metabolism.

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