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Updated: Sep 25, 2026

Live-cell Imaging of Lysosomal Membrane Permeabilization During Necroptosis
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Live-cell Imaging of Lysosomal Membrane Permeabilization During Necroptosis

Published on: November 14, 2025

Lactate couples metabolic state to necroptosis across pathological and physiological conditions

Naijin Zhang1, Xinyue Huang2, Saien Lu2

  • 1Department of Cardiology, The First Hospital of China Medical University, Shenyang, Liaoning, China; Institute of Health Sciences, China Medical University, Shenyang 110122, Liaoning, China; Department of Central Laboratory, the First Hospital of China Medical University, Shenyang, China.

Cell Metabolism
|September 23, 2026
PubMed

Keywords:
PCAFRIPK3influenza A virus infectionischemia-reperfusion injurylactatelactate dehydrogenasemetabolic regulation of cell deathmuscle regenerationnecroptosisprotein lactylation

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