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Initial experience with a donor egg bank
James W Akin1, Katrina A Bell, Diana Thomas
1Department of Obstetrics and Gynecology, University of Kentucky College of Medicine, Lexington, Kentucky, USA. jakin94939@aol.com
Objective:
To report on the establishment of a commercial donor egg bank (CryoEggs International, LP) and to present our initial experience from the first four patients to receive eggs.
Design:
Case report.
Setting:
Private fertility clinic.
Patient(S):
The four recipient women were aged 43, 43, 40, and 33 years. All had cycle day FSH levels greater than 25 mIU/mL. All were given the option of fresh donor egg IVF but opted to use frozen donor oocytes.
Intervention(S):
Purchased and quarantined frozen donor eggs were thawed and inseminated using intracytoplasmic sperm injection (ICSI). Subsequent embryos were transferred on day 3.
Main Outcome Measure(S):
Clinical pregnancy as defined by presence of cardiac activity.
Result(S):
There was a thawed egg survival rate of 76%, a fertilization rate of 74%, a pregnancy rate (PR) of 50%, with an average of 2.75 embryos per transfer and an implantation rate of 27%.
Conclusion(S):
Although very preliminary, these results indicate that more widespread use of frozen donor eggs obtained from a commercial egg bank may be feasible in the future, changing the landscape of donor egg IVF.
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