Related Experiment Video
Updated: Jul 17, 2026
Clinical Application of Microscope-Assisted Minimally Invasive Anterior Lumbar Interbody Fusion
Published on: June 16, 2023
In vitro study of biomechanical behavior of anterior and transforaminal lumbar interbody instrumentation techniques
Thomas K Niemeyer1, Marco Koriller, Lutz Claes
1Spine Service, Department of Orthopaedic Surgery, University Hospital Tübingen, Tübingen, Germany. thomas.niemeyer@med.uni-tuebingen.de
Objective:
To study the biomechanical behavior of lumbar interbody instrumentation techniques using titanium cages as either transforaminal lumbar interbody fusion (TLIF) or anterior lumbar interbody fusion (ALIF), with and without posterior pedicle fixation.
Methods:
Six fresh-frozen lumbar spines (L1-L5) were loaded with pure moments of +/-7.5 Nm in unconstrained flexion-extension, lateral bending, and axial rotation. Specimen were tested intact, after implantation of an ALIF or TLIF cage "stand-alone" in L2-L3 or L3-L4, and after additional posterior pedicle screw fixation.
Results:
In all loading directions, the range of motion (ROM) of the segments instrumented with cage and pedicle screw fixation was below the ROM of the intact lumbar specimen for both instrumentation techniques. A significant difference was found between the TLIF cage and the ALIF cage with posterior pedicle screw fixation for the ROM in flexion-extension and axial rotation (P < 0.05). Without pedicle screw fixation, the TLIF cage showed a significantly increased ROM and neutral zone compared with an ALIF cage "stand-alone" in two of the three loading directions (P < 0.05).
Conclusion:
With pedicle screw fixation, the ALIF cage provides a higher segmental stability than the TLIF cage in flexion-extension and axial rotation, but the absolute biomechanical differences are minor. The different cage design and approach show only minor differences of segmental stability when combined with posterior pedicle screw fixation.
