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Updated: Jul 17, 2026

Cholesterol Efflux Assay
Published on: March 6, 2012
[Cholesterol embolism: report of one case]
Carlos Dufrechou1, Santiago Cedrés, Lorena Bruno
1Clínica Médica 2, Facultad de Medicina, Universidad de la República Montevideo, Montevideo, Uruguay. jcb2002@adinet.com.uy
Abstract:
We report a 72 year-old male, that after a coronary angiogram presented pain, reduced distal skin temperature of both limbs, cyanosis of toes with preserved peripheral pulses and a rapidly progressive renal failure. Afterwards, the patient suffered a sudden bilateral amblyopia and hematochezia. Cholesterol embolism was confirmed with a skin biopsy and fundoscopy. A colonoscopy showed a possible ischemic colitis. After six months of follow up, the patient lost the distal phalanges of three toes, and renal failure stabilized, with a serum creatinine of 2.5 mg/dl. The diagnosis of cholesterol embolism is often missed, but it has a one year mortality of 80% and the presence of renal failure is the main prognostic indicator. Other prognostic indicators are the presence of high blood pressure, previous renal failure and peripheral artery disease.
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