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Updated: Jul 17, 2026
A Computational Modeling Approach to Investigate the Influence of Hyperthermia on the Tumor Microenvironment
Published on: December 1, 2023
The study of whole-body chemohyperthermic tumour treatment by extracorporeal circulation
Ge Bin1, Wang Shuyi, Qian Feng
1Medical Instrumentation College of University of Shanghai for Science and Technology, 200093, Shanghai, China.gb13992@hotmail.com.
Abstract:
Chemohyperthermic tumor treatment has developed quite rapidly over the past 20 years, and its therapeutic effect is widely known from clinical practice. More recently it has been realized that whole-body chemohyperthermic tumor treatment by extracorporeal circulation is quite a unique approach with which the patient's blood is withdrawn from femoral artery through a peristaltic pump to a heat-exchanger and then back to the patient's femoral vein. Tumor cells can be effectively killed when the temperature of the blood is controlled at about 42°. It has been proven that the extracorporeal chemohyperthermia is an effective alternative in malignant tumor treatment, especially for those who have missed the best therapeutic opportunities or whose cancer cells have recurred or propagated.
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