Related Experiment Video
Updated: Jul 17, 2026

Preparation of Light-responsive Membranes by a Combined Surface Grafting and Postmodification Process
Published on: March 21, 2014
Photo-triggering of the membrane gates in photo-responsive polymer for drug release
Jae Kyoo Lee1, Hoeun Lee, Eunje Jang
1Interdisciplinary Program of Biomedical Engineering, Seoul National University, Seoul, Korea; Nano-Bioelectronics and Systems Research Center, Seoul National University, Seoul, Korea.
Abstract:
The use of light stimulus for triggering drug is a promising method for accurate drug delivery. A new approach using azopolymer membrane and laser holography was investigated for developing light-triggering drug delivery system. Polymeric drug delivery system was prepared by covering azopolymer membrane on a drug agent. Holographic laser interference generated surface relief grating pattern on the azopolymer surface. The widths and depths of gates on the polymer membrane were easily modified by adjusting incident angle and irradiation time. Ar laser made the polymeric membrane permeable to the drug agent and release it in a solution. This result indicated that the azopolymer and laser holography would provide a strong foundation for the light-triggering drug delivery system.
Related Concept Videos
Modified-Release Drug Delivery Systems: Stimuli-Activated
Modified-Release Drug Delivery Systems: Classification

