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Updated: Jul 17, 2026
Simultaneous Transcranial Alternating Current Stimulation and Functional Magnetic Resonance Imaging
Published on: June 5, 2017
Spatial frequency dependence of the human visual cortical response to temporal frequency modulation studied by fMRI
A Mirzajani1, M A Oghabian, N Riyahi-Alam
1Department of Optometry, Iran University of, Medical Sciences and now PhD student with Department of Physics and, Biomedical Engineering, Tehran University of Medical Sciences (e-mail: mirzajani@sina.tums.ac.ir).
Abstract:
The brain response to temporal frequencies (TF) has been already reported, but with no study for different TF in respect to various spatial frequencies (SF). fMRI was performed by 1.5T GE-system in 14 volunteers during checkerboard visual stimulation, with TFs of 4, 6, 8 and 10Hz in low and high SFs of 0.5 and 8cpd. The averaged percentage BOLD signal changes demonstrated the amplitude of the fMRI response to different TFs which was maximally at 6Hz for high SF of 8cpd, and at 8Hz for low SF of 0.5cpd. The results are useful for vision therapy (such as the treatment of Amblyopia) and for fMRI applications incorporating visual tasks.
