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Updated: Jul 17, 2026
Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting
Published on: March 25, 2019
Detection of colon cancer by laser induced Fluorescence and Raman spectroscopy
Xiaozhou Li1, Xinyu Li, Ming Lei
1Physics Department, Shenyang Ligong University, Shenyang 110168, China; Applied Physics Institute, Dalian University of Technology, Dalian, 116023, China.
Abstract:
Laser-induced fluorescence and Raman spectroscopy of serum for detect colon cancer was investigated in this paper. The difference to serum spectrum was discovered. Three Raman peaks were consistently observed from normal blood serum emission using 488.0nm and 514.5nm excitation of an Ar-ion laser. While no Raman peak or slight Raman peaks were detected from colon cancer's cases. In addition, the red shift of fluorescence peak and decrease of fluorescence intensity are founded after samples radiated by laser. 65 colon cancer cases are investigated in this paper. Through three parameters we obtained an accuracy of 83.5% compared to clinical diagnosis. These results have important reference values to explore the method of Raman spectrum and for diagnosis of cancer.
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