Modeling the diffusion of nitric oxide produced by neuronal cells in brain ischemia
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Updated: Jul 17, 2026
2-Vessel Occlusion/Hypotension: A Rat Model of Global Brain Ischemia
Published on: June 22, 2013
Yang Yong1, Ning Gang-Min, Gan Zhuo-Hui
1Department of Biomedical Engineering, Zhejiang University (yuqun campus), Hangzhou 310027, P.R. China.
Abstract:
Mathematical models of NO diffusion were established to investigate the role of nitric oxide produced by neuronal cells in brain ischemia. Results showed that NO synthesized at early stage of brain ischemia could diffuse to a far more distant than that of a resting state. We speculate the roles of NO produced by neuronal cells in brain ischemia might have two different effects, depending on its concentration.
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