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Updated: Jul 17, 2026

A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways
Published on: May 9, 2016
Chaotic dynamics of ventilatory flow in humans
Marc Wysocki1, Marie-Noelle Fiamma, Christian Straus
1Laboratoire de Physiopathologie Respiratoire, Service de Pneumologie et Réanimation, Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris and with Hamilton Medical AG, Via Nova, CH-7403 Rhäzuns, Switzerland. Phone 00 41 79 660 62 30; fax: 00 41 79 660 60 20;
Abstract:
The present study provides further insights into the chaotic nature of the ventilatory behaviour in spontaneously breathing heal thy humans by applying the noise titration method t o ventilatory flow signals gathered in this s e t t i n g . In five subjects with normal breathing pattern and end-tidal CO2, the noise titration method gave a positive noise limit ranged from 6 to 43%. Our study shows that the noise titration technique does find chaos in the ventilatory behaviour o f healthy humans at rest, therefore opening the way to further investigations.
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