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Related Experiment Videos

An implantable multifunctional needle type biosensor with integrated RF capability.

Nan-Fu Chiu1, Jmin-Min Wang, Lung-Jieh Yang

  • 1Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan; Institute of Biomedical Engineering, National Taiwan University, Taipei, Taiwan.

Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
|February 7, 2007
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This study presents an implantable wireless biosensor for continuous glucose and cholesterol monitoring in critical care settings. The device utilizes microelectromechanical systems (MEMS) and radio frequency (RF) technology for real-time metabolite tracking.

Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Electrical Engineering

Background:

  • Continuous monitoring of glucose and cholesterol is crucial for managing patients in intensive care.
  • Existing monitoring methods often require frequent blood draws, causing patient discomfort and potential infection risk.
  • Development of implantable, wireless biosensors can overcome these limitations.

Purpose of the Study:

  • To develop an implantable, multifunctional biosensor for simultaneous in vivo monitoring of glucose and cholesterol.
  • To integrate radio frequency (RF) wireless circuitry for continuous data transmission.
  • To evaluate the performance of the developed biosensor system for short-term monitoring in critical care.

Main Methods:

  • Fabrication of micro needle sensors using silicon-based Microelectromechanical Systems (MEMS) technologies.

Related Experiment Videos

  • Integration of electropolymerized biomolecules and conducting polymers for amperometric biosensor construction.
  • Hybrid Complementary Metal-Oxide-Semiconductor (CMOS) processes for fabricating RF transmitter/receiver and data converter circuitry.

    • Main Results:

    • Successful development of an implantable needle-type biosensor capable of measuring both glucose and cholesterol.
    • Integration of 433 MHz RF wireless circuitry for data transmission.
    • Demonstration of a biocompatible Parylene coating with specific openings for electrode activity.

    Conclusions:

    • The developed implantable wireless biosensor offers a promising solution for continuous in vivo metabolite monitoring in emergency and intensive care units.
    • The combination of MEMS fabrication and CMOS circuitry enables a compact and efficient monitoring device.
    • Further studies are warranted to assess long-term performance and clinical utility.