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Assessment of Immunologically Relevant Dynamic Tertiary Structural Features of the HIV-1 V3 Loop Crown R2 Sequence by ab initio Folding
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Three-dimensional structure of HIV-1 VIF constructed by comparative modeling and the function characterization

Wei Lv1, Zhenming Liu, Hongwei Jin

  • 1State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100083, China.

Organic & Biomolecular Chemistry
|February 8, 2007
PubMed
Summary

Understanding HIV-1 accessory protein VIF is key to new therapies. Researchers modeled VIF and its complex, revealing structural insights crucial for blocking viral infectivity and survival.

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