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Related Experiment Videos

Leptospirosis masquerading as infectious enteritis.

Alona Paz1, Shelli Krimerman, Israel Potasman

  • 1Infectious Diseases, Bnai Zion Medical Center, Rappaport Faculty of Medicine, Technion, Haifa, Israel.

Travel Medicine and Infectious Disease
|February 13, 2007
PubMed
Summary
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Leptospirosis, a tropical zoonotic disease, should be considered in travelers presenting with fever and gastrointestinal issues. Early diagnosis and treatment are crucial for reducing severe illness and mortality.

Area of Science:

  • Infectious Diseases
  • Tropical Medicine
  • Microbiology

Background:

  • Leptospirosis is a widespread zoonotic disease caused by *Leptospira* spirochetes, prevalent in tropical regions.
  • Early diagnosis and treatment are critical for mitigating severe morbidity and mortality associated with leptospirosis.
  • Travelers returning from endemic areas may present with non-specific symptoms, complicating diagnosis.

Purpose of the Study:

  • To highlight the importance of considering leptospirosis in the differential diagnosis of febrile travelers with gastrointestinal symptoms.
  • To present a case study illustrating the diagnostic challenges and successful treatment of leptospirosis in a traveler.

Main Methods:

  • Case report of a 30-year-old Israeli traveler returning from Thailand.

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  • Clinical presentation included fever, chills, vomiting, and diarrhea.
  • Diagnostic workup involved serological confirmation of leptospirosis, with elevated creatinine noted.
  • Main Results:

    • The traveler presented with symptoms suggestive of gastrointestinal illness but had an unexpectedly high creatinine level.
    • Serological tests confirmed leptospirosis.
    • The patient recovered after appropriate medical intervention.

    Conclusions:

    • Leptospirosis should be included in the differential diagnosis for travelers returning from endemic areas with fever and gastrointestinal complaints.
    • Elevated creatinine can be an important indicator, broadening the diagnostic scope beyond typical travelers' diarrhea.
    • Prompt recognition and management are key to favorable outcomes in travel-associated leptospirosis.