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Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats
Published on: January 21, 2020
Complex regional pain syndrome in stroke patients
Hilal Kocabas1, Funda Levendoglu, Onder Murat Ozerbil
1Department of Physical Medicine and Rehabilitation, Selcuk University Meram Faculty of Medicine, Konya, Turkey.
Summary
Complex regional pain syndrome-I affects nearly half of stroke patients within 28 weeks. Early intervention targeting shoulder mobility and spasticity is crucial for prevention.
Area of Science:
- Neurology
- Rehabilitation Medicine
- Pain Management
Background:
- Complex regional pain syndrome-I (CRPS-I) is a debilitating condition affecting the upper extremity.
- Hemiplegic patients post-stroke are at high risk for developing CRPS-I.
- Understanding the incidence and contributing factors is vital for effective management.
Purpose of the Study:
- To determine the incidence of CRPS-I in the upper extremity of hemiplegic stroke patients.
- To identify factors influencing the development of CRPS-I within the first 28 weeks post-stroke.
Main Methods:
- A longitudinal study followed 82 hemiplegic stroke patients.
- Patients were assessed at 2, 6, 14, and 28 weeks post-stroke.
- Outcome measures included range of motion, subluxation, spasticity (Ashworth score), muscle strength (Motricity index), motor recovery (Brunnstrom stages), and depression scores.
Main Results:
- The incidence of CRPS-I was 48.8% within the first 28 weeks.
- Significant correlations were found between CRPS-I and subluxation, spasticity, muscle strength, motor recovery, and depression.
- Key factors identified include shoulder subluxation, reduced range of motion, shoulder muscle spasticity, and muscle weakness.
Conclusions:
- CRPS-I is highly prevalent in hemiplegic stroke patients.
- Interventions aimed at improving glenohumeral joint range of motion, strengthening shoulder muscles, and reducing spasticity are recommended for CRPS-I prevention.
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