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Published on: March 30, 2018
Intraocular lymphoma metastasis from larynx
T Iwase1, K Sugiyama, M Takahira
1Toyama Prefectural Central Hospital, Toyama, Japan. Tsuyoshilwase@aol.com
European Journal of Ophthalmology
|February 13, 2007
Summary
This case highlights rare laryngeal diffuse large B cell lymphoma (DLBCL) spreading to the eye. Prompt diagnosis and combined treatment of ocular metastasis led to vision recovery.
Area of Science:
- Oncology
- Ophthalmology
- Neurology
Background:
- Diffuse large B cell lymphoma (DLBCL) is an aggressive non-Hodgkin's lymphoma (NHL).
- Laryngeal involvement is uncommon, and ocular dissemination is exceptionally rare.
Observation:
- A 69-year-old man presented with blurred vision and vitreous infiltration.
- Ocular examination revealed cellular infiltration and increased opacities in the vitreous.
Findings:
- Cytopathologic examination of vitreous specimens confirmed DLBCL, identical to laryngeal and cerebellar primary tumors.
- Intraocular lesions were diagnosed as metastases of laryngeal DLBCL.
- Combined chemotherapy and radiotherapy resolved chorioretinal lesions and restored vision.
Implications:
- This case underscores the importance of considering intraocular metastasis in laryngeal DLBCL.
- Ophthalmologists and oncologists must be vigilant for rare presentations of NHL.
- Early detection and multimodal treatment are crucial for managing ocular NHL metastasis.
