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Published on: April 28, 2016
Verbal short-term memory in individuals with chromosome 22q11.2 deletion: specific deficit in serial order retention
Steve Majerus1, Martial Van der Linden, Vérane Braissand
1Experimental Psychology and Cognitive Neurosciences Research Unit, Department of Cognitive Sciences/Cognitive Psychopathology Sector, University of Liège, Liège, Belgium. smajerus@ulg.ac.be
Abstract:
Many researchers have recently explored the cognitive profile of velocardiofacial syndrome (VCFS), a neurodevelopmental disorder linked to a 22q11.2 deletion. However, verbal short-term memory has not yet been systematically investigated. We explored verbal short-term memory abilities in a group of 11 children and adults presenting with VCFS and two control groups, matched on either CA or vocabulary knowledge, by distinguishing short-term memory for serial order and item information. The VCFS group showed impaired performance on the serial order short-term memory tasks compared to both control groups. Relative to the vocabulary-matched control group, item short-term memory was preserved. The implication of serial order short-term memory deficits on other aspects of cognitive development in VCFS (e.g., language development, numerical cognition) is discussed.
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