Related Experiment Video
Updated: Jul 17, 2026

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
Published on: March 24, 2023
Lymphomatoid contact dermatitis induced by gold earrings
Alberto Conde-Taboada1, Elena Rosón, Virginia Fernández-Redondo
1Dermatology Department, Complexo Hospitalario de Pontevedra, Pontevedra, Spain. albertoct@mixmail.com
Abstract:
Metallic gold has long been regarded as a relatively safe material when in contact with the skin and mucosal membranes, with only sporadic reports of allergic contact dermatitis or stomatitis. This is probably due to its stability and low tendency to ionization. Lymphomatoid reactions have been described in cutaneous responses to several products. We report a patient who developed bilateral nodules on the earlobes at the sites of piercing earrings. Histologically, these lesions presented a lymphomatoid appearance, with a T-cell diffuse infiltrate. The patch test demonstrated a strong reaction to 1% gold sodium thiosulfate.
Related Concept Videos
Immunogold Electron Microscopy
Drug Toxicity: Allergic Reactions
Hypersensitivity Reactions: Delayed Hypersensitivity Reactions
Hypersensitivity Reactions: Immune-Complex Reactions
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Graves' Disease I: Introduction
