Mixed epithelial and stromal tumor of the kidney: a case report

The descriptive term "mixed epithelial and stromal tumor of the kidney" was recently proposed for a group of renal tumors characterized histologically by a mixture of stromal and epithelial proliferation. It is a rare benign neoplasm of the kidney which has been reported under various names such as adult type mesoblastic nephroma or others. We report a case of mixed epithelial and stromal tumor in a 47 yr old female patient presenting as a partly cystic and partly solid renal mass. Microscopically, the tumor exhibited spindle cell component in solid portion and epithelial proliferation around microcystic areas. Immunoreactive profiles and ultrastructural examination suggested myofibroblastic nature of the stromal cells. We believe this case exemplifies a unique adult renal tumor displaying both epithelial and stromal neoplastic component and has a few unusual features worthy of attention.