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Updated: Jul 17, 2026

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Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
Published on: July 14, 2023
[Diffuse pulmonary calcifications caused by hyperparathyroidism in a renal transplant recipient]
T Langenegger1, P A Diener, M Diethelm
1Departement Innere Medizin, Kantonsspital St. Gallen, Schweiz.
Deutsche Medizinische Wochenschrift (1946)
|February 15, 2007
Summary
In patients with chronic renal failure, consider hyperparathyroidism as a cause of pulmonary calcifications, even without respiratory symptoms. Early diagnosis and treatment are crucial for managing this condition.
Area of Science:
- Nephrology
- Endocrinology
- Pulmonology
Background:
- Chronic renal failure (CRF) can lead to secondary hyperparathyroidism.
- Progressive renal failure may be associated with extraskeletal calcifications.
Observation:
- A 53-year-old male with CRF post-renal transplant developed muscle weakness and pain.
- Elevated parathormone (PTH) and calcium levels were noted.
- Chest X-ray showed diffuse pulmonary calcifications.
Findings:
- The patient was diagnosed with tertiary hyperparathyroidism.
- Surgical resection of parathyroid glands resolved muscular symptoms but not pulmonary calcifications.
- Pulmonary calcifications in CRF patients warrant consideration of hyperparathyroidism.
Implications:
- Hyperparathyroidism-induced pulmonary calcifications can occur in CRF patients, with or without respiratory symptoms.
- Prompt recognition of hyperparathyroidism is vital for managing pulmonary complications in renal failure.
- Prognosis depends on the underlying disease and management of calcifications.
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